We have dealt with internal destruction of supplemental enzymes once they enter the acid environment of our stomach. It’s nice to know that vegetable-based enzymes, such as those found in Bio88+ (Plus), actually thrive in our stomach and intestines. But…can proteases be dangerous? Used appropriately, these enzymes pose no danger to the consumer. The biggest problem with enzymes is the inhalation of large quantities of enzyme dust by people who work around enzymes a great deal, or getting larg.