Which company has the best affiliate program? How do I choose the best affiliate program? Can you help me pick an affiliate program? I am often asked these questions. And, the answer many people expect is : the program that pays the most. However, the point that many rookie affiliates miss is that just because mortgage, gambling, and credit card programs are paying the most per sale or per lead dosen't mean that you will ever make any money promoting their products. In fact, the overwhelming m.