Manuel F. Casanova
The Neuroscientist, October 2006; vol. 12, 5: pp. 435-441.
Abstract
Autism is a condition manifested as abnormalities of relatedness, communication, range of interests, and repetitive behaviors. Despite alarming prevalence estimates and exhortations to research, little is known regarding its pathophysiology. Recent reports of a putative minicolumnopathy explain changes in brain size, gray/white matter ratios, and interareal connectivity. This article summarizes possible links between minicolumns and other topics—cortical modularity, age of onset, gliosis, and genetics—relevant to the pathophysiology of autism.
Post je objavljen 06.10.2010. u 07:43 sati.