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Generic name: bupropion extended release; Brand/Trade names: Wellbutrin XL, SR, Zyban; Dosages: 150 mg, 300 mg extended release tablets. Pharmacy Author: Omudhome Ogbru, PharmD Pharmacy and Medical Editor: Jay W. Marks, MD. GENERIC NAME: bupropion BRAND NAME: Wellbutrin, Wellbutrin SR, Wellbutrin XL. See independent test results for Wellbutrin_vs_Generic A once-a-day (XL) bupropion XL by some patients switched to a . And two twice-a-day (SR. I have taken Wellbutrin XL for two years and it has taken care of I had the same experience with Teva Budeprion 300mg xl. I had been taking a for buproprion SR. Best Answer: Sustained vs. extended release. Wellbutrin SR lasts for a shorter time. You have to take it twice a day. Wellbutrin XL slowly releases medication.