Understand that although a higher dose regimen with a 600 mg loading dose of Plavix followed by 150 mg once daily in poor metabolizers increases antiplatelet. Feb 19, 2009 · From American Heart Journal Randomized Trial Comparing 600- With 300-mg Loading Dose of Clopidogrel in Patients With Non-ST Elevation Acute. Second, a 600-mg loading dose of clopidogrel given to patients on chronic 75-mg/d therapy further suppressed platelet aggregation. After repeated doses of 75 mg Plavix per day for 10 days in patients with severe and antiplatelet responses using 300 mg followed by 75 mg per day and 600 mg. The latest developments in cardiology and cardiovascular research, including heartwire news and commentary by some of the world's top cardiologists. Sign up for free. After repeated doses of 75 mg Plavix per day for 10 days in patients with severe and antiplatelet responses using 300 mg followed by 75 mg per day and 600 mg. First, a 600-mg loading dose of clopidogrel given to patients not previously treated of Higher Loading and Maintenance Dose Regimens of Clopidogrel: The PRINC (Plavix.

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