In the 1930s, the pioneering geneticist J. B. S. Haldane noticed a peculiar inheritance pattern in families with long histories of haemophilia. The faulty mutation responsible for the blood-clotting disorder tended to arise on the X chromosomes that fathers passed to their daughters, rather than on those that mothers passed down. Haldane subsequently proposed1 that children inherit more mutations from their fathers than their mothers, although he acknowledged that “it is difficult to see how this could be proved or disproved for many years to come”.

That year has finally arrived: whole-genome sequencing of dozens of Icelandic families has at last provided the evidence that eluded Haldane. More­over, a study published in Nature finds that the age at which a father sires children determines how many mutations those offspring inherit2. By starting families in their thirties, forties and beyond, men could be increasing the chances that their children will develop autism, schizophrenia and other diseases often linked to new mutations. “The older we are as fathers, the more likely we will pass on our mutations,” says lead author Kári Stefánsson, chief executive of deCODE Genetics in Reykjavik. “The more mutations we pass on, the more likely that one of them is going to be deleterious.”

Full story: Nature.com

For a career, what's a technician pay?

I like to look like a person. It drives me crazy when you see women in movies playing teachers, and they have biceps. It totally takes me out of the movie. I start thinking, Wow, that actress playing this part really looks great! -- Emma Stone

I'm a fan of horror movies, especially the classics, such as Dracula, Frankenstein, and The Mummy. The list includes The Bride of Frankenstein. One of my critics over this movie, however, is the very short screen appearance of the titular character. She was in it in for only a scant few minutes, just in time for the ending. See the clip, that's pretty much all you get to see her:



So should this classic movie be re-imagined to give the first lady of horror a lot more screen time?

bride of frankenstein plus size costume

The nearly bankrupt U.S. Postal Service on Thursday reported losses of $57 million per day in the last quarter and warned it will miss another payment due to the U.S. Treasury, just one week after its first-ever default on a payment for future retiree health benefits.

From April to June, losses totaled $5.2 billion, up $2.1 billion from the same period last year.

The mail agency said it is being hurt significantly by mounting expenses for future retiree health benefits. Those expenses, mandated by Congress in 2006, made up $3.1 billion of the post office's quarterly loss, while workers compensation tacked on another $1.1 billion in expenses. The agency's operating loss was $1 billion, mostly due to declines in first-class mail.

Full story: http://news.yahoo.com/postal-reports-5-2b-loss-3rd-quarter-132412758.html

For most non-medical people, the term "apnea" is most familiar when coupled with the word "sleep," and refers to a dangerous condition in which people inadvertently stop breathing while asleep. But the word literally means a temporary cessation of breathing and it is practiced (on purpose) around the world by an international community of extreme athletes — a brotherhood that now includes magician and stuntman David Blaine. On the set of The Oprah Winfrey Show on April 30, Blaine broke the world record by holding his breath for 17 minutes and 4 seconds — proving that just how temporary apnea can be is a question of training, endurance and will.

Read more: http://www.time.com/time/health/article/0,8599,1736834,00.html

It’s the latest for extreme ultra-Orthodox Jewish men who shun contact with the opposite sex: Glasses that blur their vision, so they don’t have to see women they consider to be immodestly dressed.

In an effort to maintain their strictly devout lifestyle, the ultra-Orthodox have separated the sexes on buses, sidewalks and other public spaces in their neighborhoods. Their interpretation of Jewish law forbids contact between men and women who are not married.

Walls in their neighborhoods feature signs exhorting women to wear closed-necked, long-sleeved blouses and long skirts. Extremists have accosted women they consider to have flouted the code.


Read more: http://www.nydailynews.com/news/world/israel-new-modesty-glasses-orthodox-jewish-men-blur-women-line-sight-article-1.1133397#ixzz23F1RmFIR

Scientists have found the biggest and oldest reservoir of water ever--so large and so old, it’s almost impossible to describe.

The water is out in space, a place we used to think of as desolate and desert dry, but it's turning out to be pretty lush.



Full story: http://www.fastcompany.com/1769468/scientists-discover-oldest-largest-body-water-existence-space

Astronomy compels the soul to look upwards and leads us from this world to another. -- Plato

An officer had been shot multiple times but was expected to survive, said Greenfield Police Chief Bradley Wentland. There are reports of other casualties but no confirmed numbers.

Chief Wentland said one suspect had been shot, but more gunmen might still be on the loose inside the temple.

Full story: http://www.bbc.co.uk/news/world-us-canada-19138754

After a shooting spree, they always want to take the guns away from the people who didn't do it. I sure as hell wouldn't want to live in a society where the only people allowed guns are the police and the military. -- William S. Burroughs

So, it looks like we're not going to be able to sleep for the next month if we're going to get through this because shortly after signing off last night we got word that Paul had brought along a little surprise last night for the moviegoers at the Aero Theatre in Santa Monica. In Contention was first to report that before a 7:30pm screening of "The Shining," theatre staff announced there would be a "secret screening" afterwards and anyone who wanted to stay was welcome. Afterwards guests were treated to the first public screening anywhere in the world of "The Master," projected, yes, in 70mm. Paul and Maya were in attendance for the film which reportedly plays roughly 2 hours and 10 minutes 2 and a half hours long.



Full story: http://cigsandredvines.blogspot.ca/2012/08/the-master-premieres-secretly-in-la.html

A film is never really good unless the camera is an eye in the head of a poet. -- Orson Welles

A 19-year-old girl in Rajasthan on Friday killed herself by jumping in front of a train for not being allowed to study engineering, police said.

In her suicide note, Pooja Singh Kumawat said she was unable to pursue her dream of becoming an engineer because she was a girl, police said.

Full story: http://ibnlive.in.com/news/girl-denied-permission-to-study-kills-self/278250-3-239.html

I think a lot of what is going on with kids who get pushed too far and attempt either murder or suicide is that they are trying to deal with their own non-existence for the people who are supposed to care most for them. -- Richard Russo

Apple Inc., one of the world's most secretive companies, is finding there's a price in pushing its grievances against rival Samsung Electronics Co. in federal court: disclosure.

In just the first few days of its patent trial this week, Apple has publicly discussed how it created the iPhone and iPad, showed early designs of the devices and described intimate details about its product team.

Full story: http://online.wsj.com/article/SB10000872396390443687504577567421840745452.html?mod=WSJ_hps_LEFTTopStories

A lot of companies have chosen to downsize, and maybe that was the right thing for them. We chose a different path that if we kept putting great products in front of customers, they would continue to open their wallets. -- Steve Jobs

Recently, our own Bruce Jacobs wrote about how the coverage of the 2012 Olympic Games was just fine, and how nobody should be airing their grievances about it, which many have taken to the web to do. However, if you don’t like tape delays, web streams that freeze or are blurry on many occasions, or have even one iota of interest in seeing nations other than the United States compete, you would disagree with Bruce’s point of view.

Full story: http://1045theteam.com/american-tv-neglected-the-saddest-story-in-the-olympics/

I think after the 2008 Olympics I wasn't really satisfied with the outcome knew I had to change some things

A team of astronomers has detected the "death cry" of a star being devoured by a supermassive black hole. The black hole had been sitting quietly -- almost lying in wait, as it were -- until its gravity reached out and shredded a passing star, pulling the star into its death grip and causing it to emit a characteristic signal. "You can think of it as hearing the star scream as it gets devoured, if you like," said astronomer Jon Miller of the University of Michigan, lead author of a report appearing in Science Express.

Full story: http://www.latimes.com/news/science/sciencenow/la-sci-sn-shredded-star-cry-20120803,0,2245446.story

It is clear to everyone that astronomy at all events compels the soul to look upwards, and draws it from the things of this world to the other. -- Plato

A PHOTOGRAPH of a dark grey shape rising out of the water has been hailed as the clearest picture yet of the elusive Loch Ness Monster.



Loch Ness cruise boat operator and veteran Nessie hunter George Edwards yesterday published his photograph, which drew praise from a fellow monster expert, who described it as the best evidence that Nessie exists.

See full story.

I love all of mythology and rules pertaining to all of the monsters, but I like to go the extra step. -- Stephen Sommers

News has surfaced of scheduled shooting locations for the second Thor movie from Marvel, Thor: The Dark World. Icelandic film site Svarthofdi reports that Iceland will be a primary shot location for the sequel, which reportedly will take place for the most part in the mythical world of Asgard.



As the world of Thor is heavily inspired by Norse pagan mythology, Iceland seems like a perfect spot to shoot the film, and director Alan Taylor certainly has experience in shooting in Iceland, having shot parts of the second Game of Thrones series in the country, and returning there for the upcoming third series.

Full story: http://www.filmophilia.com/2012/08/03/thor-the-dark-world-to-shoot-in-iceland/

I love comic books and I love anime. -- Samuel L. Jackson

Following the Deepwater Horizon explosion and spill in 2010, BP
used more than 1.8 million gallons of chemical dispersants in an effort
to break up the oil. The dispersants also wiped out plankton, according
to a new study.



Full story: http://grist.org/news/use-of-dispersants-at-bp-spill-may-have-wiped-out-middle-of-the-gulf-food-web/

Continue reading up on Libor and memory improvement techniques.

I love kei cars. They are exactly the original intent of the automobile:
and object to move people and goods around efficiently. A bonus feature
is that they are attractive, the Wagon R has been around since 1993 and
let’s just point out it’s origins are Suzuki. Like a killer tomato or a
funny cat photo the Wagon R has taken on a life of it’s own, breeding
and replicating and absorbing entire countries in the process. Small
primarily FWD 5 door, with matching number of seats, the little wagon
lives up to it’s “R” title in a wholesome way. The letter denominates
it’s Radical approach. Shove everyone and everything on top of the drive
train. Build up not out.



Full story: http://speedhero.wordpress.com/2012/08/01/radical-2/

Read up on Facebook and Hot Booties slippers.

Central bankers
and regulators will hold talks in September on whether the troubled
global Libor interest rate can be reformed or whether it is so damaged
that the benchmark of borrowing costs should be scrapped.

Bank of England Governor Mervyn
King told fellow central bankers in a letter that it was "very clear
that radical reforms of the Libor system are needed".

Full story: http://www.reuters.com/article/2012/07/19/us-banking-libor-idUSBRE86H1IV20120719

Read up on the Shark Navigator vacuum cleaner and Olympic boxing.

In company filings published this week, it said 8.7% of its 955 million active users might not be real.

Duplicate profiles made up 4.8% of the users, user-misclassified accounts amounted to 2.4%, and 1.5% of users were described as "undesirable".

The estimate came at a time of growing concern about the value of marketing on the platform.

Full story: http://www.bbc.com/news/technology-19093078

Learn about Marie Osmond's weight loss and Arctic rainforest.

Iran's Ali Mazaheri cried foul when the heavyweight was
disqualified after being warned three times for persistent holding
against Cuban Jose Larduet Gomez despite leading by two points going
into the second round.

"It was a fix. I could have got a bronze easily if it hadn't been for
that," an irate Mazaheri, who walked out of the ring before the
decision was officially announced, said.

Full story: http://uk.eurosport.yahoo.com/news/olympic-boxing-judges-accused-fixing-011120870.html

Read about bowling and leather armors.

Drilling of the seabed off Antarctica has revealed that rainforest grew
on the frozen continent 52 million years ago, scientists said Thursday,
warning it could be ice-free again within decades.

The study of sediment cores drilled from the ocean floor off
Antarctica's east coast revealed fossil pollens that had come from a
"near-tropical" forest covering the continent in the Eocene period,
34-56 million years ago.

Full story: http://www.bangkokpost.com/news/world/305639/drilling-discovers-ancient-antarctic-rainforest

Read up on techs and the best Van Halen songs.